Difference between enzyme and hormone

Enzyme and hormones are the two terms we used. There is so many difference between the enzyme and the hormones. Enzyme and hormones are the chemicals which produced in our body. Enzyme and hormone both have different function in our body.
Here the difference between the enzyme and the hormones.


Enzyme
Hormone
Definition
Enzyme is the chemical produced by the body which acts as biocatalyst into the body.
Hormone is chemically produced into the body regulates the activity of certain cells or organs.
Site of Secretion
Hormone secreted by the exocrine gland.
Hormones are secreted by the endocrine gland.
Release
Enzymes act at the place where they are released into the body.
Hormones are circulated in body through the blood and act
Function
It regulates the biochemical reaction. Enzyme break the carbohydrate, protein, and lipids are into small molecules, transform it into the chemical energy which is used
Hormones regulate many activities like digestion, metabolism, growth, reproduction, moods, electrolytic balances etc. It gives the signal to cell to perform the activity.
Nature
Enzyme is the protein which may contain metal molecules.
Hormones are made up of protein and steroid 
Molecular Weight
Enzyme have high molecular weight
Hormones have low molecular weight
Example
Oxidoreductase, Transferase, Hydrolase etc
Thyroid, parathyroid, TSH, Insulin etc
Factor
Affected by pH, temperature etc
Not affected by the temperature and pH.
Site of action
Enzymes form and act at the site of production
Hormones form and act at different sites
Structure
Enzyme does not alter the structure. It is reusable.
Hormones get destroyed so it cannot be reused
Disease
possibility
Chances of occurring disease are less due to enzyme dysfunction
Chances of disease are more due to hormone dysfunction
Diffusion
They are nondiffusible through the cell membrane.
They are diffusible through cell membrane.
Prosthetic Group
Enzyme contains coenzyme and cofactor as prosthetic group.
Hormone does not have prosthetic group.

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